Generic Name: chlorzoxazone (klor ZOX a zone)
Brand names: Parafon Forte DSC, ...show all 8 brand names.
What is chlorzoxazone?
Chlorzoxazone is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain.
Chlorzoxazone is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.
Chlorzoxazone may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about chlorzoxazone?
Before taking chlorzoxazone, tell your doctor if you have liver disease. You may need a lower dose or special monitoring during therapy.
Chlorzoxazone can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of chlorzoxazone.
What should I discuss with my healthcare provider before taking chlorzoxazone?
You should not use this medication if you are allergic to chlorzoxazone.
Before taking chlorzoxazone, tell your doctor if you have liver disease. You may need a lower dose or special monitoring during therapy.
This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether chlorzoxazone passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take chlorzoxazone?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Take the medicine with a full glass of water.
Clorzoxazone is only part of a complete program of treatment that may also include rest, physical therapy, or other pain relief measures. Follow your doctor's instructions.
Store chlorzoxazone at room temperature away from moisture and heat.
See also: Chlorzoxazone dosage (in more detail)
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. An overdose of chlorzoxazone can be fatal.
Overdose symptoms may include nausea, vomiting, diarrhea, drowsiness, dizziness, headache, muscle weakness, shallow breathing, or fainting.
What should I avoid while taking chlorzoxazone?
Chlorzoxazone can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of chlorzoxazone. Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by chlorzoxazone. Tell your doctor if you regularly use any of these medicines, or any other muscle relaxer.
Chlorzoxazone side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using chlorzoxazone and call your doctor at once if you have any of these serious side effects:
nausea, stomach pain, low fever, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
black, bloody, or tarry stools;
coughing up blood or vomit that looks like coffee grounds; or
feeling like you might pass out.
Less serious side effects may include:
drowsiness, dizziness, tired feeling;
restlessness;
slightly discolored urine; or
mild skin rash or bruising.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Chlorzoxazone Dosing Information
Usual Adult Dose for Muscle Spasm:
250 to 750 mg orally 3 to 4 times a day.
The dosage may be reduced as the condition of the patient improves.
Usual Pediatric Dose for Muscle Spasm:
125 to 500 mg orally 3 to 4 times a day.
Alternative dosing: 20 mg/kg/day in divided doses 3 to 4 times a day.
What other drugs will affect chlorzoxazone?
There may be other drugs that can interact with chlorzoxazone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
More chlorzoxazone resources
- Chlorzoxazone Side Effects (in more detail)
- Chlorzoxazone Dosage
- Chlorzoxazone Use in Pregnancy & Breastfeeding
- Drug Images
- Chlorzoxazone Drug Interactions
- Chlorzoxazone Support Group
- 10 Reviews for Chlorzoxazone - Add your own review/rating
- chlorzoxazone Advanced Consumer (Micromedex) - Includes Dosage Information
- Chlorzoxazone Prescribing Information (FDA)
- Chlorzoxazone Professional Patient Advice (Wolters Kluwer)
- Chlorzoxazone Monograph (AHFS DI)
- Chlorzoxazone MedFacts Consumer Leaflet (Wolters Kluwer)
- Parafon Forte DSC Prescribing Information (FDA)
Compare chlorzoxazone with other medications
- Muscle Spasm
Where can I get more information?
- Your pharmacist can provide more information about chlorzoxazone.
See also: chlorzoxazone side effects (in more detail)
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